
Biocompatible
A natural structural protein, not a synthetic polymer. Silk fibroin derived from Bombyx mori, woven into a comfortable, breathable mesh that naturally conforms to tissue contour.
Proudly Supporting


SYLKE® Skin Closure is a single-use, sterile, woven silk fibroin mesh strip coated on one side with a pressure-sensitive adhesive. The adhesive surface is covered by a removable release liner with a pre-slit tab.
Woven silk fibroin mesh
A natural structural protein, not a synthetic polymer. Silk fibroin derived from Bombyx mori, woven into a comfortable, breathable mesh that naturally conforms to tissue contour.
Pressure-sensitive adhesive
Bonds immediately on contact; simply press to secure. Not made with natural rubber latex. Contains no cyanoacrylate.
Removable release liner
Pre-slit release liner with a 1.5" tab for controlled, sequential placement along the wound. Covers the adhesive surface until application.
Single-use and sterile. Each strip is provided in an individually sealed pouch. Lengths and widths shown to relative scale; layer spacing exaggerated for illustration.
Dry
Thoroughly cleanse and dry the wound to prepare skin for proper adhesion.
Open
Open the sterile pouch and remove SYLKE® Skin Closure.
Measure
Measure the length of the wound. Allow for 1 cm over each end of the wound edges.
Trim
Using clean scissors, trim the strip to the appropriate length.
Peel
Peel back the pre-slit tab on the release liner to expose the pressure-sensitive adhesive.
Anchor
Anchor the strip with the exposed adhesive at least 1 cm beyond the wound’s edge.
Apply
While slowly peeling back the release liner, apply the strip directly over the wound.
Press
Once applied, press along the entire length of the strip to secure the device.
The Final Step, The First Impression

SYLKE®
Application

SYLKE®
Removal

🌱
A natural structural protein, not a synthetic polymer. Silk fibroin derived from Bombyx mori, woven into a comfortable, breathable mesh that naturally conforms to tissue contour.

👋
Pressure-sensitive adhesive that bonds immediately on contact; simply press to secure. Not made with natural rubber latex. Contains no cyanoacrylate.

🩹
Pre-slit release liner with a 1.5" tab for controlled, sequential placement along the wound. Covers the adhesive surface until application.

💦
Water-resistant; avoid soaking or prolonged immersion.

💪
Designed to hold together well-approximated skin edges and protect the wound.

🗓️
Can be worn for up to two weeks.

🤝
Indicated for topical closure and coverage of thoroughly cleansed simple lacerations and minor cuts, where it may be used as the primary skin closure. SYLKE® is also indicated for topical closure and coverage of post-surgical skin incisions in which deeper layers have been closed, where it is used as an adjunct to sutures or staples.

A natural structural protein, not a synthetic polymer. Silk fibroin derived from Bombyx mori, woven into a comfortable, breathable mesh that naturally conforms to tissue contour.

Pressure-sensitive adhesive that bonds immediately on contact; simply press to secure. Not made with natural rubber latex. Contains no cyanoacrylate.

Pre-slit release liner with a 1.5" tab for controlled, sequential placement along the wound. Covers the adhesive surface until application.

Water-resistant; avoid soaking or prolonged immersion.

Designed to hold together well-approximated skin edges and protect the wound.

Can be worn for up to two weeks.

Indicated for topical closure and coverage of thoroughly cleansed simple lacerations and minor cuts, where it may be used as the primary skin closure. SYLKE® is also indicated for topical closure and coverage of post-surgical skin incisions in which deeper layers have been closed, where it is used as an adjunct to sutures or staples.
SYLKE® begins its journey in India, the birthplace of Ayurvedic medicine. Here, we ethically harvest silk fibroin from family-tended mulberry groves, honoring centuries of healing heritage. Our process is certified Cradle to Cradle™—ensuring it is cruelty-free, pesticide-free, and fully biodegradable. By carefully removing the outer sericin layer, we reveal the pure fibroin core, a naturally occurring protein recognized for its strength and biocompatibility.
In Northern Italy, a region renowned for textile elegance, our raw silk is transformed by master craftsmen. Through a process of precise twisting and spooling, fibers are woven on advanced looms into a proprietary medical-grade mesh. This collaboration of tradition and technology creates a material that balances exceptional tensile strength with a delicate, breathable finish.
Advanced manufacturing brings SYLKE® to life in the United States. From lamination in New Hampshire to final conversion in Southern California, every step is executed under strict clean-room conditions. We apply medical-grade adhesive, slit to exact specifications, and subject every unit to rigorous seal testing. This ensures a sterile, flawless product that meets the highest standards of safety before it ever leaves our facility.
Engineered for the demands of the modern operating room, SYLKE® Skin Closure delivers biocompatible skin closure. Order today with complimentary FedEx 2Day® shipping in the USA, just in time for your next case.
32cm, 24cm, or 16cm











Ships within 1 business day.
2-Year Shelf Life
Free FedEx 2Day® Shipping
Available box configurations.
| SKU | Description | Size/EA | Quantity | UOM | EA/BX |
|---|---|---|---|---|---|
| SYL-WC-32-010 | SYLKE® Skin Closure | 32cm x 2.5cm | 1 | BX | 10 |
| SYL-WC-32-050 | SYLKE® Skin Closure | 32cm x 2.5cm | 1 | BX | 50 |
| SYL-WC-24-010 | SYLKE® Skin Closure | 24cm x 3.4cm | 1 | BX | 10 |
| SYL-WC-24-050 | SYLKE® Skin Closure | 24cm x 3.4cm | 1 | BX | 50 |
| SYL-WC-16-010 | SYLKE® Skin Closure | 16cm x 2.5cm | 1 | BX | 10 |
| SYL-WC-16-050 | SYLKE® Skin Closure | 16cm x 2.5cm | 1 | BX | 50 |
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October 2025
October 24, 2025 SYLKE® Skin Closure was named a recipient of the Industry Innovation Award at the 2025 American Association of Hip and Knee...
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July 2025
July 15, 2025 The designation provides Premier member hospitals and health systems with access to SYLKE® Skin Closure through one of the nation's largest...
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September 2024
Allure recognized SYLKE® Skin Closure in its annual Best of Beauty Awards, selecting it for the Breakthrough designation. Allure, the Condé Nast beauty publication,...
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