Nature’s Oldest Biomaterial

Silk Fibroin

Silk, one of the oldest biomaterials known to humanity, has a remarkable history in the world of medicine. Its roots can be traced back to ancient China and Egypt, where it served as both a wound dressing and suture material. At SYLKE®, we stand at the forefront of reimagining silk for the demands of modern medicine, focusing on harnessing one of its most valuable proteins: fibroin.

Silkworm silk consists of two essential proteins: fibroin and sericin. Fibroin, the structural backbone of silk fibers, imparts strength and resilience, while sericin acts as a protective coating. In recent years, groundbreaking advancements in silk science have unveiled a diverse range of biomolecular properties that position fibroin as an exceptional material for wound regeneration and tissue engineering.
Silk Fibroin's Natural

Strength and Flexibility

SYLKE® leverages the extraordinary strength and biocompatibility of pure silk fibroin—a natural material with tensile strength comparable to steel by weight. Our wound closure system combines a breathable silk fibroin mesh for optimal flexibility and comfort with a gentle, secure pressure-sensitive adhesive for extended wear. The protective peel-off liner enables seamless application with no need for additional adhesives or curing time in the operating room.
"We chose the best." - M. Mark Mofid, MD FACS

Premium Italian Weave

Ethically sourced from the silk capital of the world, northern Italy, SYLKE® uses only the highest quality strands for its raw materials. The custom weave is designed to accommodate even the most contoured and mobile parts of the body.
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Evidence-Based Research

Proven Clinical Benefits

Extensive research demonstrates that silk fibroin enhances cellular proliferation, growth, and differentiation while facilitating the adhesion of stem cells across diverse tissue types.

Its unique combination of attributes, including exceptional mechanical strength, non-immunogenicity, and regenerative potential, makes it the perfect material that is underutilized in wound closure. In vivo studies have yielded compelling evidence, including accelerated wound healing and superior skin regeneration when compared to conventional hydrocolloid dressings.